Effect of different components in milk on bioavailability of phenolic acid in humans

Not Applicable

Completed

• Conditions: utrition; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN02642603
• Lead Sponsor: China Agricultural University (China)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-09-14
• Last Update Posted: 3 July 2017

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Healthy males or females
2. Aged 18 - 65

Exclusion Criteria

1. Severe obesity, Body Mass Index (BMI) > 32 kg/m2
2. Metabolic and endocrine diseases
3. Malabsorption syndromes
4. Current smoking or smoking cessation for < 6 months
5. Alcohol abuse (> 40 g alcohol/d)
6. Pregnancy/lactation
7. Food allergy
8. Milk intolerance
9. Vegetarian
10. Blood donation or blood transfusion less than 3 months prior to the study
11. Major surgery within the 3 months preceding the study
12. Simultaneous participation in another drug trial and use of dietary supplements or any form of medication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Phenolic acids in plasma and urine measured at 1, 2, 3, 4, 6, 8 hours after intervention

Secondary Outcome Measures

Name	Time	Method
1. Serum triacylglycerols, total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol <br>2. Total antioxidant capacity in plasma<br>3. Resistance of serum lipids to oxidation<br>The outcomes will be measured at 1, 2, 3, 4, 6, 8 hours after intervention