Incorporation of omega-3 fatty acids

Not Applicable

Completed

• Conditions: Healthy subjects; Not Applicable

• Registration Number: ISRCTN46532656
• Lead Sponsor: Southampton University Hospitals NHS Trust (UK)

Brief Summary

2016 Results article in https://www.ncbi.nlm.nih.gov/pubmed/27424661 results

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-08-08
• Study Completion: 2012-12-31
• Last Update Posted: 27 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Healthy
2. Aged 18 to 45 years
3. Body mass index 20 to 32 kg/m2
4. Not consuming fish oil or other oil supplements
5. Not eating more than one oily fish meal per week
6. Willing to adhere to the study protocol
7. Being able to provide written informed consent

Exclusion Criteria

1. Aged < 18 or > 45 years
2. Body mass index < 20 or > 32 kg/m2
3. Being diabetic (type 1 or type 2)
4. Use of prescribed medicine to control inflammation
5. Chronic gastrointestinal problems (e.g. IBD, IBS, celiac disease, cancer)
6. Allergic to fish
7. Participation in another clinical trial
8. Use of fish oil or other oil supplements

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in EPA content of plasma phospholipids from study entry to week 12

Secondary Outcome Measures

Name	Time	Method
<br> 1. Change in EPA content of each of the other plasma lipid pools and of mononuclear cells and red blood cells from study entry to week 12<br> 2. Change in DHA content of each of the plasma lipid pools and of mononuclear cells and red blood cells from study entry to week 12<br> 3. Change over time in blood concentrations of inflammatory markers<br>