Comparison of dexamethasone vs ketorolac as an adjutant to levobupivacaine in ultrasound guided transverse abdominis plane block for postoperative analgesia in patients undergoing lower segment caesarean section under neuraxial anesthesia
Trial Snapshot
- Phase
- Phase 1/2
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 84
- Locations
- 1
- Primary Endpoint
- Compare the analgesic efficacy of dexamethasone vs ketorolac as an adjutant to levobupivacaine in ultrasound guided transverse abdominis plane block for postoperative analgesia in patients undergoing lower segment caesarean section surgery
Study Overview
Brief Summary
In this study, we would like to compare the analgesic efficacy ofdexamethasone and ketorolac as an adjutant to levobupivacaine in ultrasound guided transverse abdominis plane block for postoperative analgesia in patients undergoing lower segment caesarean section under neuraxial anesthesia.
Intraoperatively, BP and PR measured at 0, 5, 10, 15 and 30 mins.
Post operatively PR and BP measured at every 20 mins for first 2 hours and at 4,6,12 and 24 hours.
Post operative VAS score in 2,4, 6,12 and 24 hours.
Patient satis Score measured after 24 hours.
Duration of onset of pain and motor power in hours.
Thank you
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- Female
Inclusion Criteria
- •American Society of Anaesthesiologists (ASA) physical status I and II, patients undergoing lower segment caesarean section, Patient’s willingness to participate in study.
Exclusion Criteria
- •Patient’s refusal, BMI more than 35, Allergy to opioids, amide group of local anaesthetics and non steroidal anti-inflammatory drugs, Coagulation derangement or bleeding disorder, Infection at the site of block, Patients with cardiovascular pulmonary or neurological diseases, Patients converted to general anaesthesia after giving subarachnoid block, Uncontrolled intraoperative bleeding.
Outcomes
Primary Outcomes
Compare the analgesic efficacy of dexamethasone vs ketorolac as an adjutant to levobupivacaine in ultrasound guided transverse abdominis plane block for postoperative analgesia in patients undergoing lower segment caesarean section surgery
Time Frame: Post operative VAS score in 2,4,6,12 and 24 hours. | Duration of onset of pain in Hours | Duration of onset of motor power in Hours.
Secondary Outcomes
- Post operative hemodynamics , patient satisfaction score, VAS score(Post operative Blood pressure and Heart rate at 2,4,6,12 and 24 hours.)
Investigators
Suhas M
Saveetha medical college and hospital