Aortic Valve Calcium Scoring in Various Etiologies of Aortic Stenosis among Thai patients

Not Applicable

Recruiting

• Conditions: Patient with aortic stenosis diagnosed by echocardiogram with mild, moderate and severe aortic stenosis; Aortic stenosis; Aortic valve calcium score; Coronary calcium score; MDCT aortic valve calcium score; Rheumatic heart disease

• Registration Number: TCTR20200521002
• Lead Sponsor: Faculty of medicine, Chiangmai university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-21
• Study Completion: 2020-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

1. Age > 18 yr
2. Patients with mild, moderate and severe aortic stenosis diagnosed with echocardiogram.
3. MDCT scan will be performed within a period of 3 months after enrollment in prospective cases (with informed consent)
For retrospective cases : aortic stenosis (all degree of severity) with MDCT data within a period of 3 months
4. Concordance severity grading of AS

Exclusion Criteria

1. Children <18 years of age
2. Endocarditis
3. Classical and Paradoxical low flow †low gradient severe aortic stenosis
4. Incomplete / non-diagnostic echocardiographic image quality
5. Pregnant women

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnostic accuracy of aortic valve calcium score 1 day Aortic valve calcium score (ROC)

Secondary Outcome Measures

Name	Time	Method
Prevalence of subclinical atherosclerosis 1 day Coronary calcium score ,Cut off point for diagnosing severe aortic stenosis in various etiologies 1 day Aortic valve calcium score ,Etiology of aortic stenosis among Thai patients 1 day Number and percentage of etiology of aortic stenosis among Thai patients