Different doses of dexmedetomidine for conscious sedation during awake nasotracheal fiberoptic intubation fiberoptic

Not Applicable

• Conditions: Surgery; patient comfort, intubating condition and hemodynami stability during conscious sedation; Nervous System Diseases

• Registration Number: PACTR201712002863123
• Lead Sponsor: Faculty of Medicine, Aswan University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-12
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

patients with ASA patients status I and II

Exclusion Criteria

Patients with obesity more than 30% above the ideal body weight, patients refusal,gastroesophageal reflux, uncontrolled blood pressure, ischemic heart diseases, diabetic, asthmatic, severe bradycardia or any type of A-V block on ECG,coagulapthy, hepatic, renal dysfunction thrombocytopenia, hyperactive air way diseases, , history of drug maluse,and a long term use of benzodiazepines or antidepressant drugs, any neurological disorders or mental retardation, pregnancy, nasal polyp, history of allergy to any used medication, any apparent airway abnormalities with mallampati score ¿ III(7), thyromental distance ¿ 6 centimeters and history of laryngeal or pharyngeal surgeries all were excluded from our study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The Observer¿s Assessment of Alertness and Sedation Scale (OAA/S) and level of discomfort during nasal fiberoptic intubation

Secondary Outcome Measures

Name	Time	Method
). Hemodynamic parameters including Heart Rate (HR), Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP), SpO2 and EtCO2 were also detected during preoxygenation, fiberscope insertion (1, 2, 3, 4, 5and 8 min. intervals) and endotracheal intubation(1, 2, 3, 4, 5and 8 min. intervals)