Comparison between two drugs (Gabapentin and Pregabalin) for post-operative pain management after spine surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Patients posted for elective lumbar laminectomy surgery under general anaesthesia.
- Registration Number
- CTRI/2018/04/013305
- Lead Sponsor
- B R Singh Hospital and Centre for Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients willing to comply with the post-operative follow up evaluations.
Exclusion Criteria
Known allergy to any of study medications
Renal insufficiency, peptic ulcer disease or history of bleeding diathesis or liver disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the postoperative analgesic efficacy of gabapentin 900 mg versus pregabalin 300mg in patients undergoing lumbar laminectomy surgery.Timepoint: Post-operatively at 1 hour, 2 hours, 4 hours, 6 hours, 12 hours and 24 hours.
- Secondary Outcome Measures
Name Time Method To assess and compare the haemodynamic parameters, efficacy in reducing the level of preoperative anxiety and level of postoperative sedation and side effects after administration of both drugs.Timepoint: Intraoperatively at induction of anaesthesia and 30 minutes till the end of surgery. <br/ ><br>Post-operatively at 1 hour, 2 hours, 4 hours, 6 hours, 12 hours and 24 hours.