The new guidline of corneal transplantation based on the inflammatory Cytokines in the Tears.
Not Applicable
Recruiting
- Conditions
- eyes that have candidate for the corneal transplantation
- Registration Number
- JPRN-UMIN000015070
- Lead Sponsor
- Tokyo Dental College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
The exclusion criteria included limbal stem cell deficiency or previous glaucoma and corneal transplantatioin surgery.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to evaluate the inflammatory Cytokines (IL-1alpha,IL-1beta,IL-2,IL-4,IL-6,IL-8,IL-17A,TNF) in the Tears. Corneal thickness
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What role do tear inflammatory cytokines like IL-6 and TNF-α play in corneal graft rejection mechanisms?
How does cytokine-guided corneal transplantation compare to standard immunosuppressive protocols in post-surgical outcomes?
Which tear cytokine biomarkers predict immune compatibility and long-term success in corneal transplant recipients?
What adverse events are associated with cytokine-targeted interventions in corneal transplantation, and how are they managed?
Are there synergistic effects of combining cytokine monitoring with anti-inflammatory agents like cyclosporine in corneal graft survival?