Corneal transplantation by ultra-thin DSAEK: thinner grafts, better vision?

Completed

• Conditions: Corneal endothelial failure; 10047518; 10015957

• Registration Number: NL-OMON39225
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-10-01
• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 66

Inclusion Criteria

Endothelial dysfunction caused by pseudophakic or aphakic corneal edema, (Fuchs*) endothelial dystrophy, a minimum patient age of 18 years, and best spectacle-corrected visual acuity (BSCVA) lower than 20/50.

Exclusion Criteria

Previous corneal transplantation, human leukocyte antigen typed keratoplasty, and patients who are unable to communicate properly or to understand instructions.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcome measure is best corrected visual acuity. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcome measures are contrast acuity, astigmatism, quality of vision,<br /><br>endothelial cell loss, incidence of graft rejection, primary graft failure,<br /><br>cornea donor loss due to preparation, and generic and vision-related quality of<br /><br>life.</p><br>