HEALING EFFICACY OF MORINGA OLEIFERA LEAVES POWDER IN INTRAORAL WOUND HEALING : A COMPARATIVE STUDY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Wound Healing effect of Moringa oleifera leaves powder on intraoral wounds.
研究概览
简要总结
This split-mouth clinical study aims to evaluate the woundhealing effects of Moringa oleifera also known as drumstick leaf powder, in postoperative wounds. The minimum sample size is 60 sites, and they are randomly assigned using computer software into two groups. One group will serve as the control site, and the other as the test site. One site will receive only periodontal dressing, while the other site will receive periodontal dressing combined with Moringa oleifera leaf powder.
Participants will be selected based on specific inclusion criteria, which are pocket depth equal to or greater than four millimeters, age above eighteen years, presence of more than twenty teeth, and at least thirty percent of the teeth affected by periodontitis. The exclusion criteria include a history of any systemic disease, pregnancy or lactation, smoking, having undergone periodontal treatment within the past six months, and the use of antibiotics, anti-inflammatory drugs, or mouthwash in the last six months.
Soft tissue healing will be assessed at one week and one month after the procedure using the Early Healing Index developed by Wachtel 2003 and the Healing Index by Landry in 1988. Patient satisfaction regarding wound healing and postoperative discomfort will be evaluated using a 5point Likert scale. Ethical approval will be obtained before the start of the study
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Individuals having pocket depth 04 millimetre or more than 04 millimeters, more than 20 teeth present in the oral cavity, with 30 percent of teeth having Periodontitis.
排除标准
- •Participants with a history of any systemic disease,Pregnant and lactating females,Participants with a history of smoking,Participants who have undergone any periodontal treatment in the past 06 months prior to enrollment,History of antibiotic or antiinflammatory or mouthwash use in past 06 months prior to enrollment.
结局指标
主要结局
Wound Healing effect of Moringa oleifera leaves powder on intraoral wounds.
时间窗: at 01 week and 01 month followup respectively
次要结局
- Participants satisfaction level regarding wound healing and postoperative discomfort assessed by Likert scale 1932(At 01 month follow up)
研究者
Dr Nehil Saran
King George Medical College