MedPath

TBTC Study 23: Treatment of HIV-Related Tuberculosis Using a Rifabutin-Based Regimen

Not Applicable
Completed
Conditions
HIV Infections
Tuberculosis
Registration Number
NCT00023361
Lead Sponsor
Centers for Disease Control and Prevention
Brief Summary

Primary objective:

To determine the rate of confirmed treatment failure and relapse with an intermittent rifabutin-based regimen for the treatment of isoniazid and rifamycin-susceptible HIV-related tuberculosis (TB).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
215
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Rate of confirmed treatment failure and relapse
Secondary Outcome Measures
NameTimeMethod
Safety and tolerability
Response of HIV RNA to TB treatment
Paradoxical reactions

Trial Locations

Locations (23)

Central Arkansas Veterans Health System

🇺🇸

Little Rock, Arkansas, United States

LA County/USC Medical Center

🇺🇸

Los Angeles, California, United States

University of California, San Francisco

🇺🇸

San Francisco, California, United States

Denver Department of Public Health and Hospitals

🇺🇸

Denver, Colorado, United States

Washington, D.C. VAMC

🇺🇸

Washington, District of Columbia, United States

Chicago VA Medical Center (Lakeside)

🇺🇸

Chicago, Illinois, United States

Hines VA Medical Center

🇺🇸

Hines, Illinois, United States

Johns Hopkins University School of Medicine

🇺🇸

Baltimore, Maryland, United States

Boston Medical Center

🇺🇸

Boston, Massachusetts, United States

New Jersey Medical School

🇺🇸

Newark, New Jersey, United States

Scroll for more (13 remaining)
Central Arkansas Veterans Health System
🇺🇸Little Rock, Arkansas, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.