Perfluorocarbon Liquid vs. Posterior Retinotomy During Pars-plana Vitrectomy for Rhegmatogenous Retinal Detachment

Not Applicable

Completed

• Conditions: Rhegmatogenous Retinal Detachment

• Registration Number: NCT06919211
• Lead Sponsor: Benha University

Brief Summary

Purpose To evaluate the outcomes of perfluorocarbon liquid (PFCL) versus posterior retinotomy (PR) during Pars plana vitrectomy (PPV) for Rhegmatogenous retinal detachment (RRD), focusing on anatomical success, visual acuity, intraocular pressure (IOP), and complications.

Methods This is a prospective randomized controlled trial that included 58 eyes with RRD, divided into Group A (PFCL, n = 29) and Group B (PR, n = 29). Preoperative assessments included best-corrected visual acuity (BCVA), IOP, axial length, lens status, macula status, and PVR grade. Outcomes were evaluated at 1 week, 1 month, 2 months, and 3 months postoperatively. Primary outcomes included retinal reattachment rates and the number of operations; secondary outcomes included BCVA, IOP changes, complications like cataract development, retinal redetachment, epiretinal membrane (ERM) formation, and single-surgery success.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-15
• Primary Completion: 2024-07-30
• Study Completion: 2024-07-30
• Status Verified: 2025-03
• Study First Submitted: 2025-03-29
• Study First Submitted QC: 2025-04-04
• Last Update Submitted: 2025-04-04
• Study First Posted: 2025-04-09
• Last Update Posted: 2025-04-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Retinal reattachment rates	One month, Two months, and Three Months
Number of operations	One month, Two months, and Three Monthes

Secondary Outcome Measures

Name	Time	Method
Best-corrected visual acuity (BCVA)	One month, Two months, and Three Monthes
Intraocular pressure (IOP)	One month, Two months, and Three Monthes
Complications like cataract development, retinal redetachment, epiretinal membrane (ERM) formation, and single-surgery success	One month, Two months, and Three Monthes

Trial Locations

Locations (1)

Ebsar Eye Center; 🇪🇬 Cairo, Egypt