The effect of Nigella Sativa on oligomenorrhea and amenorrhea in patients with polycystic ovary syndrome

Not Applicable

• Conditions: Polycystic ovarian syndrome.; Polycystic ovarian syndrome

• Registration Number: IRCT2016041827455N1
• Lead Sponsor: School of Traditional Medicine, Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 68

Inclusion Criteria

Diagnosis of Polycystic Ovary syndrome by gynecologist, according to the National Institute of Health’s criteria; women aged 18-38 years old with irregular periods; having informed consent; Non-consumer of any hormonal medication and Metformin for at least three months prior the study.
Exclusion criteria: Using anti-hypertensive, anti-cholesterol, anti- diabetic, insulin-sensitizing,medication; using aspirin and other anti-clotting medications, oral contraceptive and the anti-prostaglandin medications, parallel consumption of other herbal medications for disease treatment; patient with uncontrolled high blood pressure history, brain stroke, heart attack, cancer, cardiovascular disorders, liver disease, renal and thyroid disorders, type 1 or 2 diabetes; pregnancy and lactation; smoking.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
0ccurance of Menstrual bleeding. Timepoint: Before the intervention,1, 2, 3 and 4 months after the intervention. Method of measurement: Ask the patient.;Duration of menstural bleeding. Timepoint: Before intervention and 1,2,3, 4 month after intervention. Method of measurement: Ask the patient and complete tracking form.;Menstrual blood volume. Timepoint: Before intervention and1,2, 3, 4 month after intervention. Method of measurement: Pictorial Blood Loss Assessment Chart (PBAC).

Secondary Outcome Measures

Name	Time	Method
Menstrual cycle length. Timepoint: Before intervention and1,2, 3, 4 month after intervention. Method of measurement: Ask the patient and complete tracking form.;Serum LH. Timepoint: Before intervention and 3 month after intervention. Method of measurement: Serum analysis by ELIZA.;Total Testosterone. Timepoint: Before intervention and 3 month after intervention. Method of measurement: Serum analysis by ELIZA.