IRCT20140907019073N5
Not yet recruiting
未知
A Comparative Study of the Efficacy of single and double Centrifuged platelet rich plasma and placebo (normal saline injection) on Pain, ROM and Physical Function of Patients with Knee Osteoarthritis: A Double Blinded Controlled Randomized Trial with a Three-Month Follow –up
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Knee Osteoarthritis.
- Sponsor
- Iran University of Medical Sciences
- Enrollment
- 45
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with grade 2 or 3 primary osteoarthritis of the knee as determined by the Kellgren and Lawrence criteria. (Associated with knee pain, morning stiffness less than 30 minutes, crepitus on movement and radiological signs of osteoarthritis include joint space loss, subchondral bone sclerosis and the formation of osteophytes in knee)
- •Patients aged 50\-75 years.
- •Patients who have persistent knee pain for at least six months and with an intensity of at least 4 according to the VAS scale in activities such as going up and down stairs, sitting for long periods and squatting.
- •Patients who are able to walk independently for at least 30 meters.
- •Patients with a body mass index equal to or less than 35\.
- •The patient has full consent to participate in the study.
- •The patient has a balanced mental state.
Exclusion Criteria
- •The patient has a history of intra\-articular injection in the knee during the last six months.
- •The patient has neuromuscular diseases.
- •The patient has a history of acute traumatic injury to other ligaments and structures of the knee joint with the approval of a specialist.
- •The patient has a history of surgery or previous injury in the knee and other lower limb joints over the last year.
- •The patient has bone implants.
- •The patient has a new fracture in the lower extremities during the last year.
- •The patient has malignant tumors.
- •The patient has participated in exercise therapy and physiotherapy programs during the last three months.
Outcomes
Primary Outcomes
Not specified
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