Involvement of esophageal achalasia and achalasia-related diseases and viral infections and their regulators
Not Applicable
Recruiting
- Conditions
- esophageal achalasia and achalasia-related diseases
- Registration Number
- JPRN-UMIN000040317
- Lead Sponsor
- Showa University Koto Toyosu Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 210
Inclusion Criteria
Not provided
Exclusion Criteria
Patients group: (1) Patients who are judged to be ineligible to perform POEM (2) Patients who are judged to be inappropriate by the doctor in charge (for example, patients in a significantly bad condition) (3) Patients who cannot obtain informed consent Control group: Patients who cannot obtain informed consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quantitative analysis of herpesvirus microRNA expression in the esophageal muscle layer of patients with esophageal achalasia or achalasia-related disease. Transcriptome analysis of infectious virus species and their regulatory molecules in the esophageal muscle layer of patients with esophageal achalasia or achalasia-related diseases.
- Secondary Outcome Measures
Name Time Method Relationship between esophageal achalasia (Type I, Type II, Type III) or patients with achalasia-related diseases and viral infection in the esophageal muscle layer and its regulatory molecules and various pathological conditions. Relationship between esophageal achalasia (Type I, Type II, Type III) or achalasia-related disease patients, identified virus species, and various pathological conditions. Serological diagnosis of viruses that can cause esophageal achalasia and other esophageal dyskinesia.