NCT00093873已完成1 期
A Phase 1, First in Human, Open-Label, Dose Finding Study Evaluating the Safety and Pharmacokinetics of AMG 706 in Subjects With Advanced Solid Tumors
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- Amgen
- 入组人数
- 71
- 主要终点
- Dose limiting toxicity
研究概览
简要总结
This study will determine the safety and pharmacokinetics of AMG 706 in subjects with advanced solid tumors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
AMG 706
Experimental
AMG 706 QD
干预措施: Anti-angiogenesis (Drug)
AMG 706
Experimental
AMG 706 QD
干预措施: AMG 706 (Drug)
结局指标
主要结局
Dose limiting toxicity
时间窗: Cycle 1
次要结局
- Dose selection(Study completion)
研究者
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