Effects of E-Cigarettes in Menthol Smokers

Not Applicable

Completed

• Conditions: Smoking Behaviors; E-cigarette Use
• Interventions: Device: JUUL E-Cigarette Device

• Registration Number: NCT05949034
• Lead Sponsor: University of Southern California

Brief Summary

The current laboratory study examines e-cigarette preferences and smoking behaviors in menthol cigarette smokers.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-05-29
• Study Start: 2019-07-01
• Primary Completion: 2020-11-14
• Study Completion: 2020-11-14
• Status Verified: 2023-07
• Study First Submitted QC: 2023-07-13
• Study First Posted: 2023-07-17
• Last Update Submitted: 2023-07-18
• Last Update Posted: 2023-07-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• Daily cigarette smoking for at least the past 2 years
• Interest in trying e-cigarettes
• Report smoking mentholated cigarettes

Exclusion Criteria

-- Pregnancy and/or breastfeeding

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
E-Cigarette Flavor 2 Condition	JUUL E-Cigarette Device	Participants will self-administer a flavored e-cigarette.
E-Cigarette Flavor 3 Condition	JUUL E-Cigarette Device	Participants will self-administer a flavored e-cigarette.
E-Cigarette Flavor 1 Condition	JUUL E-Cigarette Device	Participants will self-administer a flavored e-cigarette.

Primary Outcome Measures

Name	Time	Method
Mood - Profile of Mood States	4 hours	This measure is obtained through the completion of the Profile of Mood States. A total score will be calculated. Scores can range from 10 to 260, with the lower scores representing lower levels of mood disturbance and higher scores representing higher levels of mood disturbance.
Preference Ratings	1 hour	Self-report measures of product preference will be completed following the e-cigarette self-administration. Scores can range from 0 to 100 for the preference rating, with lower scores representing less preference and higher scores representing higher preference.
Mood - Positive Affect Negative Affect Schedule	4 hours	This measure is obtained through the completion of the Positive Affect Negative Affect Schedule. A total score will be calculated for both Positive and Negative Affect. Scores can range from 10 to 50 for both the Positive and Negative Affect, with the lower scores representing lower levels of Positive/Negative Affect and higher scores representing higher levels of Positive/Negative Affect.
Cigarette Craving	4 hours	This measure is obtained through the completion of the Brief Questionnaire of Smoking Urges. A total score will be calculated. Scores can range from 10 to 70, with the lower scores representing a lower level of cigarette craving and higher scores representing greater levels of cigarette craving.
Nicotine Withdrawal - Minnesota Nicotine Withdrawal Scale	4 hours	This measure is obtained through the completion of the Minnesota Nicotine Withdrawal Scale. A total score will be calculated. Scores can range from 0 to 32, with the lower scores representing a lower level of nicotine withdrawal and higher scores representing greater levels of nicotine withdrawal.
Nicotine Withdrawal - Wisconsin Smoking Withdrawal Scale	4 hours	This measure is obtained through the completion of the Wisconsin Smoking Withdrawal Scale. A total score will be calculated. Scores can range from 0 to 112, with the lower scores representing a lower level of nicotine withdrawal and higher scores representing greater levels of nicotine withdrawal.
Smoking Motivation	2 hours after experimental session outset	This measure is obtained through the completion of a computerized behavioral task.

Trial Locations

Locations (1)

University of Southern California; 🇺🇸 Los Angeles, California, United States