Effects of co-supplementation with probiotic and magnesium on components of microbiota-gut-brain axis including mood, intestinal barrier function and stool microbial populations in obese subjects with metabolic mood syndrome

Shiraz University of Medical Sciences0 个研究点目标入组 90 人开始时间: 待定最近更新: 2021年11月1日

适应症

试验速览

暂无简介。

•?Willing to participate in the study
•Age range of 18 to 50 years
•Body Mass Index (BMI) =30 and waist circumference (WC) more than 85cm in women and 102 cm in men
•Beck Depression Inventory (BDI) scores ranging between 17 to 40
•Not taking probiotic supplements in the last 2 months and antibiotics in the last 3 months
•Absence of chronic liver, kidney, cardiovascular, GI and infectious diseases as well as diabetes, and severe neurological and psychiatric disorders.
•Not using anti-depressants
•Not using antioxidants, omega-3 and magnesium supplements less than one month prior to study commencement
•Not regular use of steroid and non-steroid anti-inflammatory drugs
•No regular alcohol drinking or smoking, No opioid addiction
•No history of heart attack, not being pregnant or intending pregnancy, not being in breastfeeding or menopausal states.

•pregnancy, any significant change in diet or physical activity, starting new drugs or antibiotics, and not intending to continue study protocols.

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