Clinical study on the recovery of motor function and the level of BDNF in patients with ischemic stroke by Acupuncture and medicine combined with Yisui method

Not Applicable

• Conditions: schemic Stroke

• Registration Number: ITMCTR2100005001
• Lead Sponsor: The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. It is consistent with the clinical diagnostic criteria of ischemic stroke;
2. The diagnosis criteria of marrow deficiency syndrome were met;
3. With motor dysfunction;
4. Patients in convalescence (2 weeks to 3 months after onset);
5. Aged 45-80 years old;
6. The vital signs were stable, the state of consciousness and mental state were normal;
7. The modified Ashworth Scale (MAS) of upper and lower limbs was less than or equal to grade 3;
8. Volunteer to participate in the trial and sign the informed consent.

Exclusion Criteria

1. The diagnosis was not confirmed by CT or MRI;
2. Patients receiving antispasmodic therapy before hospitalization;
3. Dyskinesia caused by other nervous system diseases (such as Parkinson's disease and syndrome, brain tumor, hepatolenticular degeneration, etc.);
4. The diagnosis was hemorrhagic stroke and transient ischemic attack;
5. Combined with serious medical diseases (such as heart, liver, kidney and other important organ failure, atrial fibrillation, pulmonary embolism);
6. Patients with coma, dementia, vegetative state or mental disorder;
7. severe hypertension (systolic blood pressure equal to 180mmHg or diastolic blood pressure > 110mmHg), hypertensive encephalopathy, diabetic ketoacidosis;
8. There are fixed metal, denture, metal foreign body or pacemaker in the body.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fugl-meyer scale;

Secondary Outcome Measures

Name	Time	Method
Modified Ashworth scale;Scoring table of marrow deficiency syndrome in traditional Chinese Medicine;proBDNF\mBDNF;MBI;Diffusion tensor imaging;