Esophageal microbiota after Peroral esophageal myotomy in achalasia patients

Not Applicable

Completed

• Conditions: Diseases of the digestive system

• Registration Number: KCT0005797
• Lead Sponsor: Yonsei University Health System, Severance Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

(1) patients who were diagnosed with achalasia and planned to undergo POEM; (2) age 20-80 years;

Exclusion Criteria

(1) history of previous treatment except medication for achalasia; (2) history of chest and gastrointestinal surgery; (3) prior treatment with proton pump inhibitors or antibiotics within 8 weeks; (4) presence of active infection in oral cavity; (5) history of malignancy; (6) history of bleeding tendency or taking antithrombotics; and (7) presence of systematic disease receiving treatment.

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Esophageal microbiota

Secondary Outcome Measures

Name	Time	Method
symptom improvement, Eckardt score