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Investigate the effects of Pomegranate Extract Supplementation on Inflammation in Overweight and Obese Individuals

Not Applicable
Conditions
Overweight and obesity.
Simple obesity NOS
Registration Number
IRCT2015062722934N1
Lead Sponsor
Vice Chancellor for research of Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
48
Inclusion Criteria

Inclusion Criteria: Willingness to participation; Between the age 30-60 years old and Having a BMI within the range 25-40 kgm2; does not have a history of use of any dietary supplements within 3 months prior to the study; does not smoking or alcohol consumption; does not take any cholesterol; triglyceride as well as blood lowering medicine; does not suffer from any acute condition which needs treatment; does not suffer from metabolic stress, infection or inflammation; does not suffer from abnormal liver or kidney function; without any history of heart disease; does not take estrogen and progesterone; does not suffer from poly cyctic ovarian syndrome; not be pregnant or does not lactating.
Exclusion criteria:; meet any aforementioned condition which can exclude the participants from the study ; present any changes in the diet or physical activity.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
IL-6. Timepoint: 30 days. Method of measurement: IL-6 was measured by ELISA kits (BioCore, Germany).;MDA. Timepoint: 30 days. Method of measurement: IL-6 was measured by ELISA kits (BioCore, Germany).
Secondary Outcome Measures
NameTimeMethod
Hs-CRP. Timepoint: 30 days. Method of measurement: ELISA method using using commercial ELISA kit (Biochem, Ontario, Canada).;Glucose. Timepoint: 30 days. Method of measurement: determined through an enzymatic calorimetric method using glucose oxidase by commercial kits (Pars azmoon, Tehran, Iran).;Cholestrol. Timepoint: 30 days. Method of measurement: determined through an enzymatic calorimetric method using glucose oxidase by commercial kits (Pars azmoon, Tehran, Iran).;HDL-C. Timepoint: 30 days. Method of measurement: determined through an enzymatic calorimetric method using glucose oxidase by commercial kits (Pars azmoon, Tehran, Iran).;LDL-C. Timepoint: 30 days. Method of measurement: determined through an enzymatic calorimetric method using glucose oxidase by commercial kits (Pars azmoon, Tehran, Iran).;Insulin. Timepoint: 30 days. Method of measurement: determined through an enzymatic calorimetric method using glucose oxidase by commercial kits (Pars azmoon, Tehran, Iran).
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