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Clinical Trials/NCT01468142
NCT01468142
Completed
Not Applicable

Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure

Karolinska University Hospital1 site in 1 country6 target enrollmentFebruary 2012
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ConditionsRespiratory Distress Syndrome, AdultRespiratory Distress Syndrome, Child

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Respiratory Distress Syndrome, Adult
Sponsor
Karolinska University Hospital
Enrollment
6
Locations
1
Primary Endpoint
Course of inflammatory parameters and lung function
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is the observation of the course of

  • the mechanics of the respiratory system
  • the endexpiratory lung volume
  • and the inflammatory response in patients undergoing treatment with extracorporeal life support (ECLS) due to severe refractory respiratory failure at our department.
Registry
clinicaltrials.gov
Start Date
February 2012
End Date
December 2016
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Karolinska University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Bernhard Holzgraefe

Consultant, ECMO centre Karolinska, Principal Investigator

Karolinska University Hospital

Eligibility Criteria

Inclusion Criteria

  • •patients accepted for extracorporeal life support at our department due to the most severe forms of ARDS/respiratory failure not responding to conventional therapy.

Exclusion Criteria

  • •malignant disease with a poor prognosis
  • •massive intracranial bleeding

Outcomes

Primary Outcomes

Course of inflammatory parameters and lung function

Time Frame: end of treatment

Study Sites (1)

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