Correlation Between Pulmonary Functions and Physical Fitness in Children With β-thalassemia
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- assessment of pulmonary functions by spirometer
研究概览
简要总结
The aims of this study are:
- To determine the correlation between pulmonary functions and physical fitness in children with β-thalassemia.
- To differentiate between different types of B-thalassemia in both pulmonary functions and physical fitness
详细描述
Cohort study: cross-sectional design
A) Subjects:
Sample size estimation will be carried out to determine the recruited number of children selected randomly. Each participant's caregiver will sign a consent form authorizing the participation of their children in this study.
They will be selected based on the following:
Inclusion criteria:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •• age range from 6 to 12 years
- •children with β-thalassemia major and intermediate of both sex and control healthy children of both sex
- •They can follow instruction
排除标准
- •• Defined Cardiovascular or respiratory disorders.
- •Renal failure
- •Visual or hearing impairment, Mentally retarded children
- •Myocardial infarction within the last month
- •Unstable angina, Recent thoraco-abdominal surgery
- •Thoracic or abdominal aneurysm or Current pneumothorax
结局指标
主要结局
assessment of pulmonary functions by spirometer
时间窗: baseline - one hour for each participant
measurements difference in vital capacity and minute ventilation
physical fitness
时间窗: baseline - one hour for each participant
functional capacity by 6 minute walk test
cardiorespiratory fitness
时间窗: baseline - one hour for each participant
measure by 3 minutes step test to monitor recovery of heart rate after stress test
次要结局
未报告次要终点
研究者
Esraa Elsayed Abaas Awad
assistant lecture
Cairo University