Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure

Completed

• Conditions: Respiratory Distress Syndrome, Adult; Respiratory Distress Syndrome, Child

• Registration Number: NCT01468142
• Lead Sponsor: Karolinska University Hospital

Brief Summary

The purpose of this study is the observation of the course of

* the mechanics of the respiratory system

* the endexpiratory lung volume

* and the inflammatory response in patients undergoing treatment with extracorporeal life support (ECLS) due to severe refractory respiratory failure at our department.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-11-07
• Study First Submitted QC: 2011-11-08
• Study First Posted: 2011-11-09
• Study Start: 2012-02
• Status Verified: 2016-12
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Last Update Submitted: 2016-12-19
• Last Update Posted: 2016-12-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6

Inclusion Criteria

• patients accepted for extracorporeal life support at our department due to the most severe forms of ARDS/respiratory failure not responding to conventional therapy.

Exclusion Criteria

• malignant disease with a poor prognosis
• massive intracranial bleeding

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Course of inflammatory parameters and lung function	end of treatment

Trial Locations

Locations (1)

ECMO Centre Karolinska; 🇸🇪 Solna, Stockholm, Sweden