Sarcopenia in Patients With Heart Failure
- Conditions
- Sarcopenia
- Registration Number
- NCT06634316
- Lead Sponsor
- Maimónides Biomedical Research Institute of Córdoba
- Brief Summary
Sarcopenia is a frequent complication in patients with cancer and chronic diseases, it is characterized by decreased muscle strength and fatigue due to reduced skeletal muscle mass, which is accompanied by atrophy and decreased quality of muscle tissue. In all cases, it negatively impacts treatment tolerance, clinical outcomes and survival, in consequence, quality of life of these patients decreases while morbidity, mortality and costs increase. In this context, appropriate nutritional screening and early nutrition support are extremely recommended, to this aim, in some cases, oral nutritional supplements (ONS) are necessary; ONS could have a standard formula or be enriched with specific nutrients. There is a lack of evidence for supporting its use or the use of protein modules in other clinical conditions including patients with heart failure
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Patients with a previous admission due to HF in the previous 12 months
- Moderate or severe LVEF
- Both sexs
- Age >18 years old.
- MDRD <15 ml/min
- End-stage liver disease.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Muscle mass 6 months Changes in muscle mass
Functionality 6 months Changes in functionality determined by the up and go test
- Secondary Outcome Measures
Name Time Method Albumin 6 months Changes in serum albumin levels (g/dl)
C-RP 6 months Changes in serum C-RP (g/dl)
Trial Locations
- Locations (1)
IMIBIC
🇪🇸Cordoba, Spain
IMIBIC🇪🇸Cordoba, Spain