Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomised, controlled trial

Completed

• Conditions: Weaning from mechanical ventilation; Surgery; Ventilation

• Registration Number: ISRCTN37456640
• Lead Sponsor: Albert Einstein Hospital (Brazil)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07-16
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Adult (more than 18 years old, either sex) mechanically ventilated post-operative ICU patients.

Exclusion Criteria

1. Haemodynamic instability
2. Neurological surgeries
3. Previous pulmonary disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of weaning process. <br><br>Timepoints: <br>1. Start of ventilator triggering by the patient <br>2. Patient extubation

Secondary Outcome Measures

Name	Time	Method
1. Levels of pressure support, from the start of spontaneous breathing till extubation<br>2. Respiratory rate, from the start of spontaneous breathing till extubation<br>3. Tidal volume, from the start of spontaneous breathing till extubation<br>4. Respiratory rate/tidal volume (L), from the start of spontaneous breathing till extubation<br>5. Fraction of inspired oxygen (FIO2), positive end expiratory pressure (PEEP) levels and oxygen saturation during the weaning process, from the start of spontaneous breathing till extubation<br>6. Need of re-intubation or need of non-invasive ventilation after 48 hours of extubation