Hydrogen-rich Water and Appetite in Obesity

Not Applicable

Completed

• Conditions: Obesity

• Registration Number: NCT06722326
• Lead Sponsor: University of Novi Sad, Faculty of Sport and Physical Education

Brief Summary

The main goal of this study is to investigate how dihydrogen supplementation impacts body composition, appetite, quality of life specific to obesity, and levels of the hormone GLP-1 in men and women with obesity. This randomized controlled trial aims to explore whether dihydrogen can improve these health indicators.

Detailed Description

The primary aim of this randomized controlled trial is to evaluate the effects of dihydrogen supplementation on body composition indices, appetite, obesity-specific quality of life, and circulating GLP-1 levels in obese men and women

Study Timeline

• Study Start: 2024-05-15
• Study First Submitted: 2024-12-03
• Study First Submitted QC: 2024-12-03
• Study First Posted: 2024-12-09
• Primary Completion: 2024-12-30
• Study Completion: 2024-12-30
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-16
• Last Update Posted: 2025-03-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Age 18-65 years
• Body fat > 30% in women and > 25% in men
• Not physically active
• Informed consent signed

Exclusion Criteria

• Major chronic disease and acute injuries
• History of dietary supplement use during the past 4 weeks
• History of obesity pharmaceuticals use during the past 8 weeks
• No consent to randomization
• Participation in other studies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Appetite	Change from baseline appetite at 8 weeks	Total scores for appetite as assessed by the the Food Cravings Questionnaire (FCQ)

Secondary Outcome Measures

Name	Time	Method
Obesity-related quality or life	Change from baseline total scores for obesity-related quality of life at 8 weeks	Total scores for obesity-related quality of life as assessed by the The Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire
Body fat	Change from baseline body fat at 8 weeks	Percentage of body fat as assessed by a multifrequency bioelectrical impedance analyzer
Serum GLP-1	Change from baseline GLP-1 at 8 weeks	Serum levels of glucagon-like peptide-1 (GLP-1)

Trial Locations

Locations (1)

Applied Bioenergetics Lab; 🇷🇸 Novi Sad, Vojvodina, Serbia