Hydrogen-Rich Water and Exercise-Related Biomarkers in Men and Women Over 50 Years

Not Applicable

Completed

• Conditions: Aging
• Interventions: Dietary Supplement: Placebo; Dietary Supplement: Supplement

• Registration Number: NCT06163287
• Lead Sponsor: University of Novi Sad, Faculty of Sport and Physical Education

Brief Summary

The study investigates the impact of consuming hydrogen-rich water over a six-week period on exercise-related biomarkers among individuals aged over 50, both men and women, who undergo a resistance training program. This research aims to discern the potential benefits of hydrogen-infused water consumption concerning exercise-related markers in an aging demographic post-resistance training.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-10-01
• Study First Submitted: 2023-11-30
• Study First Submitted QC: 2023-11-30
• Study First Posted: 2023-12-08
• Primary Completion: 2024-03-31
• Study Completion: 2024-03-31
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-03
• Last Update Posted: 2024-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• Age 50 - 65 years (at least 50% would be over 60 years)
• Body mass index 18.5 - 29.9 kg/m2
• Free of major chronic diseases or acute disorders
• Resistance exercise naïve (no resistance traiing during 6 months before study commences)

Exclusion Criteria

• History of dietary supplement use during the 4 weeks before study commences
• Unwillingness to return for follow-up analysis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	One tablet of hydrogen-free supplement before breakfast and dinner
Supplement	Supplement	One tablet of hydrogen-rich supplement before breakfast and dinner

Primary Outcome Measures

Name	Time	Method
36-Item Short Form Health Survey	Change from baseline 36-Item Short Form Health Survey total score at 6 weeks	Short Form Health Survey total score, minimum and maximum possible score of between 0 and 100, with higher scores mean better outcome

Secondary Outcome Measures

Name	Time	Method
Dehydroepiandrosterone	Change from baseline serum dehydroepiandrosterone at 6 weeks	Level of dehydroepiandrosterone in serum
Grip strength	Change from baseline grip strength at 6 weeks	Muscular strength generated by one's forearm muscles
Myoglobin	Change from baseline serum myoglobine at 6 weeks	Level of myoglobin in serum
Pittsburgh Sleep Quality Index	Change from baseline Pittsburgh Sleep Quality Index score at 6 weeks	Pittsburgh Sleep Quality Index score, a score ranging from 0 to 3, with 3 indicating the greatest dysfunction

Trial Locations

Locations (1)

FSPE Applied Bioenergetics Lab; 🇷🇸 Novi Sad, Vojvodina, Serbia