CTIS2024-510752-12-00进行中(未招募)1 期
General anesthesia versus sedation with high-flow nasal cannula for the endovascular treatment of acute ischemic stroke. GHIFTS Study (General anesthesia vs High Flow nasal cannula for Thrombectomy on Stroke) - GHIFTS
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中(未招募)
- 入组人数
- 116
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 65+(—)
- 性别
- All
入选标准
- •Age greater than or equal to 18 years., NIHSS = 6 and = 25., Anterior circulation stroke with isolated or combined occlusion of: - Intracranial Internal Carotid Artery. - Middle Cerebral Artery in its M1 or M2 segments., Time of evolution from clinical onset to radiology ward admission < 6 hours, or < 24 hours since last seen asymptomatic if salvageable tissue is demonstrated on neuroimaging tests., Informed consent signed by the patient if capable, or by a family member/legal representative if the patient is not capable.
排除标准
- •Coma on admission (Glasgow Coma Scale < 8)., Baseline severe dependency status (mRS>3)., Severe/significant agitation on admission., Objective loss of airway protection reflexes or vomiting on admission., Failure to comply with fasting (6 hours of solids and 2 hours of clear liquids)., Known or suspected difficult airway on examination., Allergy or intolerance to any of the medications used for sedation or general anesthesia., Recent maxillofacial trauma/surgery., Acute cerebral hemorrhage or clear hemorrhagic transformation in the same vascular territory., Thrombopenia <50,000 or severe coagulation disturbances.
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