Relationship of Preoperative Fasting With Tricuspid Annular Plane Systolic Excursion

• Conditions: The Relationship Between TAPSE Value and Volume
• Interventions: Diagnostic Test: Tricuspid Annular Plane Systolic Excursion

• Registration Number: NCT06105866
• Lead Sponsor: Aydin Adnan Menderes University

Brief Summary

The aim of our study is to try to establish a relationship between preoperative fasting-related volume changes and tricuspid annular plane systolic excursion (TAPSE), and to determine whether there are changes in right ventricular functions due to preoperative fasting.

Detailed Description

TAPSE (Tricuspid Annular Plane Systolic Excursion) is a parameter that easily measures apex-base shortening and provides specific information about global right ventricular (RV) function. It is less dependent on optimal image quality and serves as an easily measurable criterion compared to other RV function measurements. In this study, one day before the operation, transthoracic echocardiography (TTE) will be conducted on fasting patients, and if the preoperative fasting duration is appropriate on the day of the surgery, TTE measurements will be repeated and recorded. The study aims to evaluate the relationship between TAPSE and volume and determine whether there are any changes in right ventricular functions due to preoperative fasting.

Study Timeline

• Study First Submitted: 2023-10-19
• Study First Submitted QC: 2023-10-26
• Study First Posted: 2023-10-30
• Study Start: 2024-02-11
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-01
• Last Update Posted: 2024-12-04
• Primary Completion: 2024-12-05
• Study Completion: 2024-12-05

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• ASA 1-2-3
• The patient must be between 18 and 75 years old.
• Perioperative hydration has not been administered.
• Preoperative sedatives have not been given.
• There should be no known heart disease.

Exclusion Criteria

• The patient being pregnant
• Post-cardiac surgery
• Severe pulmonary hypertension
• Severe valve disease
• Hypertrophic or dilated cardiomyopathy
• Presence of acute myocardial infarction
• Non-sinus rhythm

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients without Cardiac Disease	Tricuspid Annular Plane Systolic Excursion	Patients between the ages of 18-65 with sinus rhythm, and without valvular disease, pulmonary hypertension, acute myocardial infarction, dilated, and hypertrophic cardiomyopathy will be included in the study.

Primary Outcome Measures

Name	Time	Method
The TAPSE value is related to volume	Patients who apply to our hospital for surgery within 6 months will be included in our study. Preoperative TAPSE measurements will be taken from the patients twice, first during admission and immediately before the operation	We will measure FAC, S' velocity, TAPSE, and Myocardial Performance Index (MPI) derived from TDI to evaluate Right Ventricular (RV) systolic functions. To assess the RV diastolic function, we will measure Tricuspid E and A wave velocities, E/A ratio, and E' velocity. TAPSE will be calculated by placing an M-mode cursor along the Tricuspid Annulus and measuring the longitudinal excursion during peak systole

Trial Locations

Locations (1)

Sevil Gulasti; 🇹🇷 Aydın, Zafer, Turkey