Clinical effect of modified Guipi Decoction on language function of children with cblC methylmalonic aciduria
- Conditions
- Methylmalonic aciduria
- Registration Number
- ITMCTR2100004632
- Lead Sponsor
- The First Affiliated Hospital of Henan University of traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) It was consistent with the diagnosis of cblC type MMA of deficiency of both heart and spleen;
(2) For the clinical manifestations with abnormal language function, the assessment results of S-S language retardation test were referred to for the determination of language dysfunction;
(3) They were aged from 1 to 5 years old;
(4) The legal guardian of the child signed the informed consent and was willing to accept traditional Chinese medicine treatment and clinical investigation.
(1) There were severe visual impairment, hearing impairment, cardiovascular and cerebrovascular diseases;
(2) Patients with other diseases that seriously affect language function, such as hypothyroidism and hydrocephalus;
(3) Patients with severe infection, abnormal liver and kidney function and metabolic disorder.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method