Survival After Emergency Laparotomy in Octogenarians

Completed

• Conditions: Abdomen, Acute; Surgery--Complications; Frailty; Postoperative Complications

• Registration Number: NCT04176432
• Lead Sponsor: Haukeland University Hospital

Brief Summary

In this single-center retrospective study we wanted to investigate mortality and postoperative complications after emergency laparotomy performed in patients aged 80 years or above.

Detailed Description

Methods:

During 2015-2016 106 patients aged 80 years or above underwent emergency laparotomy at Haukeland University Hospital.

Primary outcome was mortality at 30 days. Secondary outcomes were mortality at 90 days, 1 year, postoperative complications and level of care at discharge.

The Medical records were reviewed in detail and mortality and postoperative morbidity were registered. Post-operative complications were defined according to the European Perioperative Clinical Outcome (EPCO) definitions and included if they were Clavien Dindo grade 2 or above.

Study Timeline

• Study Start: 2015-01-01
• Primary Completion: 2016-12-31
• Study Completion: 2019-01-31
• Study First Submitted: 2019-09-27
• Status Verified: 2019-11
• Study First Submitted QC: 2019-11-21
• Last Update Submitted: 2019-11-21
• Study First Posted: 2019-11-25
• Last Update Posted: 2019-11-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 106

Inclusion Criteria

• emergency laparotomy in patients 80 years or above

Exclusion Criteria

• palliative surgery
• abdominal surgery other than gastrointestinal
• abdominal surgery without midline incision

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of Deaths within 30 days after emergency laparotomy	From date of emergency laparotomy until 30 days after surgery	Mortality at 30 days after date of emergency laparotomy

Secondary Outcome Measures

Name	Time	Method
Number of Deaths within 90 days after emergency laparotomy	90 days after emergency laparotomy	Mortality at 90 days after date of emergency laparotomy
Postoperative complications	Postoperative complications registered in medical records from date of emergency laparotomy until death in hospital or discharge from hospital, whichever came first.	Number of patients having a postoperative complication as defined by the European Perioperative Clinical Outcome Definitions (EPCO) will be reported. The EPCO definitions state universal description of various common postoperative complications, like f.ex pulmonary complications, major adverse cardiac events, urinary tract infections and so on. This is a way of securing a universal approach to postoperative complications.; We will grade complications according to the Clavien Dindo classification. According to this classification postoperative complications are graded from 1 to 5, where 1 indicates least severity of complication and 5 indicating worst severity. We will report number of patients having complications from grade 2 to grade 5.
Level of care at discharge	Up to 90 days from date of emergency laparotomy.	From the medical records will be retreived information regarding dependency in activities of daily living (ADL) at discharge. Specifically will be measured number of patients discharged to own home, and number of patients discharged to nursing home facility. Also will be measured number of patients transferred to other hospital.
Number of Deaths within 1 year after emergency laparotomy	1 year after emergency laparotomy	Mortality at 1 year after date of emergency laparotomy