Does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction?

niversity of Aberdeen (UK)0 个研究点目标入组 200 人开始时间: 2011年9月29日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Men or women
•2. Aged at least 18 years to 55 years
•3. Presenting within 12 hours of the onset of chest pain who have ST segment elevation of more 1mm elevation in limb leads or 2mm elevation in two contiguous chest leads and for whom the clinical decision has been made to treat with primary PCI will be eligible for enrolment
•4. Occlusion of the culprit related artery (TIMI grade 0 or TIMI grade 1) will also be required for inclusion
•5. Eligible patients will be of North European descent

•1. Historical or ECG evidence of previous myocardial infarction
•2. Patients with prior coronary artery bypass grafting (CABG)
•3. Prior revascularization procedure where this procedure (PCI) was performed in the same territory as the current infarct
•4. Known or suspected pregnancy
•5. Contra-indications to MRI
•6. Patients with cardiac arrest or cardiogenic shock
•7. Patients with left main coronary occlusion
•8. Patients with known moderate to severe renal failure (estimated GFR < 30mls/min), or liver failure
•9. Patients with prior thrombolysis for this event

发起方

niversity of Aberdeen (UK)