Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1. Patients of the outpatient clinic of the Medical Spectrum Twente;
2. Age between 40 and 75;
Exclusion Criteria
1. Serious other disease with a low survival rate;
2. Clinical symptoms (e.g. temperature > 38,5 oC), indicating pneumonia and a thorax X-ray positive for pneumonia;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of the exacerbations. This is measured by a Body Area Network, a symptom diary and lung function (FEV1 and PEF).
- Secondary Outcome Measures
Name Time Method 1. Severity of the exacerbations. This is measured by a Body Area Network, a symptom diary and lung function (FEV1 and PEF);<br /><br>2. Relapse rate. A relapse is defined as an exacerbation that resolves due to the blinded treatment but re-occurs within 28 days of the treated exacerbation;<br /><br>3. Cost-effectiveness of treatment with antibiotics;<br /><br>4. Use of rescue-medication, recorded in the symptom diary;<br /><br>5. Quality of life, measured by the Chronic Respiratory Questionnaire and the COPD Chronic Questionnaire.