Esophageal adaptation to different textures of food comparing with ages
- Conditions
- DysphagiaSwallowing physiologyEsophageal dysphagiaEsophageal manometryEsophageal mano-fluoroscopy
- Registration Number
- TCTR20221025001
- Lead Sponsor
- The Royal College of Physicians of Thailand (RCPT)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 60
Age 20-80 years
Swallowing disturbance questionnaire (SDQ) score below 0.5
Able to follow commands
On a regular diet at home
Unable to communicate and answer the SDQ
Uncontrolled medical conditions including unstable vital signs, COPD, or asthma exacerbation
The presence of esophageal dysmotility symptoms such as heartburn, chest pain, regurgitation, chronic cough, hoarseness of voice, nausea and vomiting
History of disease or disorder that altered esophageal function such as stroke, Parkinsons disease, Alzheimer, motor neuron disease, multiple sclerosis, oropharyngeal anatomical distortion from head and neck cancer, sarcopenia, GERD, and achalasia
Chronic disease involving vital organs including heart, brain, kidney, liver, lung, CNT disease, psychiatric problems, severe OSA, poor controlled DM except for HT, DLP
BMI less than 18.5 or greater than 25 or weight loss of more than 5 percent over 6 to 12 months
History of head and neck surgery, esophageal or gastric surgery
Using prokinetics, antispasmodics, muscle relaxants, anti-cholinergic, opioids, nitrate, calcium channel blocker, antidepressant, and beta adrenergic antagonist within 1 week cannot withhold medication during the period of the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Esophageal wall distension at the beginning of study Metric of esophageal manometry
- Secondary Outcome Measures
Name Time Method Esophageal clearance at the beginning of study FLuoroscopy