Effect of ONO-8539 on Transient Lower Esophageal Sphincter Relaxation in healthy male volunteer
Not Applicable
Recruiting
- Conditions
- gastroesophageal reflux disease
- Registration Number
- JPRN-UMIN000015601
- Lead Sponsor
- Deaprtment of Gastroenterology, Osaka City University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1. Subjects who take drugs except for nasal spray within 1 week befor intervention 2. Subjects whose basal LES pressure is less than 5mmHg at HRM 3. Subjects who drink alcohol or take nicotine within 24 hours before intervention 4. Subjects who are enrolled in other clinical trials within 3 months before this study 5. Past history of GI tract surgery except for endoscopic treatment 6. Any liver, kidney, or heart diseases 7. Subjects who are not eligible for participation judged by a doctor
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The number of TLESRs
- Secondary Outcome Measures
Name Time Method