Comparison of Rhomboid Intercostal and Sub Serratus Plane Block with Erector Spinae Plane Block for perioperative analgesia in children undergoing Video Assisted Thoracoscopic Surgery under General Anaesthesia.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Total mean intraoperative fentanyl consumption in children undergoing VATS under general anaesthesia receiving either RISS block or ESP block.
研究概览
简要总结
Title of the thesis is Comparison of Rhomboid Intercostal and Sub Serratus Plane Block with Erector Spinae Plane Block for perioperative analgesia in children undergoing Video Assisted Thoracoscopic Surgery .Target population is children aged 3-10 yrs old.Study design is Randomized Controlled Trial with sample size 36 (18 in each group).Primary outcome includes total intraoperative fentanyl consumption.Secondary outcomes includes total intraoperative sevoflurane usage, Time to first rescue analgesic usage in post op, post op pain scores, Serum cortisol and IL 6 levels, number of rescue analgesic doses in first 24 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 3.00 Year(s) 至 10.00 Year(s)（—）
- 性别
- All
入选标准
- •1.American Society of Anesthesiologists(ASA)grades I,II,III .
排除标准
- •1.History of bleeding diathesis.
- •2.Children receiving anticoagulant treatment.
- •3.Infection at the region of block.
- •4.Any known allergies to local anaesthetics or opioids.
结局指标
主要结局
Total mean intraoperative fentanyl consumption in children undergoing VATS under general anaesthesia receiving either RISS block or ESP block.
时间窗: Just after completion of Surgery
次要结局
- Total mean intraoperative consumption of sevoflurane.(Just after completion of Surgery.)
- Time at which first rescue dose of analgesia is given.(Post operatively after completion of Surgery.)
- Mean post operative pain score using visual analogue scale and FLACC behavioral scale.(At 0, 3, 6, 12 and 24 hrs post operatively.)
- Mean serum cortisol and interleukin 6 levels(Preoperative baseline and 6 hrs post block administration.)
- Total number of doses of rescue analgesia doses required.(24 hrs post operatively.)
研究者
Dr Laxmi Meena
Maulana Azad Medical College