Comparative Analysis of Biomarkers in Physically Active and Sedentary College Students

University of Georgia2 个研究点分布在 1 个国家目标入组 9 人开始时间: 2024年3月11日最近更新: 2025年2月20日

适应症

干预措施

试验速览

阶段: 1 期
状态: 已完成
发起方: University of Georgia
入组人数: 9
试验地点: 2
主要终点: Ammonia

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to understand how college students' biomarkers change with a relatively short bout of moderate-intensity physical activity. The investigators are comparing biomarkers in between self-reported physically active and sedentary students in terms of their percent difference and change. The investigators are also studying physically active versus sedentary college students' mental health. This is a mentored student research project in the investigator's lab (not part of a thesis, dissertation, or other coursework requirements), where multiple students have developed research questions using the same study design.

详细描述

This study will use a two-group (sedentary versus active) pre-test, post-test study design. Following the informed consent process, participants will complete the pre-test data collection protocol including the first venipuncture blood draw for ammonia, insulin, cortisol, and c-reactive protein, first finger stick blood sample for glucose measurement, reporting of food eaten for the day as well as transportation methods to the study site. Resting heart rate will be measured.

Following a 15-minute waiting period to minimize potential effects from the blood draw, participants will walk with a study team member to a reserved elliptical machine. For the exercise component, the lab member will emphasize to the participant about maintaining the desired heart rate for moderate intensity exercise. The participant will use the elliptical for 12 minutes, without music, conversation, or general entertainment. Appropriate warm-up and cool-down is added in to the exercise time (the first two minutes and last two minutes) with preference of moderate intensity exercise lasting 8 minutes.

Participants will then walk with the study team member back to the Lab for post-test data collection. Post-test data collection follows the same procedures as pre-test data collection. Participants also will take a mental health questionnaire.

研究设计

研究类型: Interventional
分配方式: Non Randomized
干预模型: Parallel
主要目的: Basic Science
盲法: Single (Outcomes Assessor)

盲法说明

Lab processing the blood samples is blinded to participant group.

入排标准

年龄范围: 18 Years 至 34 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•This study will enroll full-time students at the investigator's university who are aged 18-34 years.
•Participants will be generally healthy participants, assessed using the 2020 Physical Activity Readiness Questionnaire (first 7 questions) as a screening tool. Individuals who answer "no" to all of the 7 questions will be deemed healthy enough to take part.
•Two balanced groups will be created based on self-reported current activity level, either sedentary (<30min/week of exercise) or meeting exercise guidelines (>=150min/week of exercise).
•Potential participants should be willing to complete the blood draws and the 12 minutes of moderate-intensity exercise on an elliptical machine.
•Potential participants should be able to speak and read the English language. This is so they will be able to understand the study protocols clearly.

排除标准

•Are allergic to nuts because the snacks provided following the blood draw may contain nut products.
•Do not have transportation and parking (if needed) to lab.

研究组 & 干预措施

Sedentary Individuals - Acute Moderate-Intensity Exercise

Experimental

8 minutes of elliptical exercise at a moderate intensity based on heart rate reserve. There will be a 2-minute warm-up and 2-minute cool down period in addition to the 8 minutes at moderate-intensity.

干预措施: Elliptical Activity (Behavioral)

Active Individuals - Acute Moderate-Intensity Exercise

Experimental

干预措施: Elliptical Activity (Behavioral)