BIOMarker study to identify the Acute risk of a Coronary Syndrome (BIOMArCS) and Hartinfarct-biomarker studie (deel II).
Recruiting
- Conditions
- Acute Coronary Syndrome (Unstable Angina, Non ST-Elevatiom Myocardial infarction and ST-elevation Myocardial Infarction)
- Registration Number
- NL-OMON27734
- Lead Sponsor
- Principal investigator: Prof. Eric Boersma, PhD, MSc, FESC. Department of Cardiology, unit Clinical Epidemiology, ErasmusMC Rotterdam, The Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 700
Inclusion Criteria
1. Complaints of typical ischemic chest pain, lasting 10 minutes or more within the preceding 24 hours prior to presentation;
2a. ECG: (Non-)persistent ST segment elevation > 1.0 mm in two or more contiguous leads or dynamic ST segment depression > 1.0 mm in two or more contiguous leads;
Exclusion Criteria
1. Myocardial ischemia precipitated by a condition other than atherosclerotic coronary artery disease (e.g. arrhythmia, severe anemia, hypoxia, thyrotoxicosis, cocaine abuse, severe valvular disease, hypotension);
2. Left ventricular ejection fraction < 30 % or end-stage congestive heart failure (NYHA class III or IV);
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is a composite of cardiovascular mortality or a clinical diagnosis of a non-fatal acute coronary syndrome during 1-year follow-up.
- Secondary Outcome Measures
Name Time Method