MedPath

Quantitative Studies of Urinary Bladder Sensation

Completed
Conditions
Interstitial Cystitis
Registration Number
NCT00903435
Lead Sponsor
Timothy Ness, MD
Brief Summary

The purpose of this study is to determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal counterirritation-related modulatory systems.

Detailed Description

To determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal counterirritation-related modulatory systems. Previous studies by the PI suggest that two populations of subjects are present in the IC population but a larger number of subjects with IC would need to be tested in order to determine if this were indeed true. Other studies have demonstrated that counterirritation-related effects are absent in several chronic pain populations including fibromyalgia and chronic headaches. Identification of a subset of IC patients or the identification of a failure of counterirritation-related effects may predict responses to therapeutic interventions.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Must be able to read and speak English
  • 19 years or older
  • IC Diagnosis
Exclusion Criteria
  • Over 65 years old
  • Pregnant
  • Children younger than 19
  • Significant cardiac disease

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The study proposes to examine the sensations that are produced by warming the skin, poking the skin, pressure on the muscles or by applying a blood pressure cuff.One and a half to two hours
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

UAB Kirklin Clinic

🇺🇸

Birmingham, Alabama, United States

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