Sensory Processing in Subjects With Painful Bladder Syndrome
Completed
- Conditions
- Painful Bladder Syndrome
- Interventions
- Other: Physical examination
- Registration Number
- NCT00903643
- Lead Sponsor
- University of Alabama at Birmingham
- Brief Summary
The purpose of this study is to determine if clinically relevant subsets exist in patients meeting the diagnosis of Painful Bladder Syndrome (PBS). Subsets suggest differential responses to treatments and if verified, this will be important for the stratification of patients in clinical studies related to PBS.
- Detailed Description
Patients with the diagnosis of painful bladder syndrome (PBS) constitute two or more phenotypes that are distinguished by differential neurophysiological processing of sensory information. Further, these differing phenotypes can be predicted by the presence or absence of the co-morbidity fibromyalgia.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
- NIDDK criteria for Painful Bladder Syndrome
- Age 19 years or older
- Must be able to read and speak English since testing materials are validated in English
Exclusion Criteria
- PBS subjects must be independent of co-existing pain disorders or use of medications
- Uncontrolled hypertension or significant cardiopulmonary disease
- No chronic daily pain
- Older than 75 years of age
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Healthy subjects Physical examination - PBS subjects Physical examination -
- Primary Outcome Measures
Name Time Method This study proposes to examine the sensations that are produced by warming the skin, poking the skin, pressure on muscles and by applying a blood pressure cuff. One and half to two hours.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Kirklin Clinic Urology Clinic
🇺🇸Birmingham, Alabama, United States