Effect of Curcumin in the prevention of Peri-procedural Myocardial Injury

Phase 1

• Conditions: Injury of heart, unspecified with or without hemopericardium; Peri-procedural Myocardial Injury.; S26.9

• Registration Number: IRCT20231125060174N1
• Lead Sponsor: Zahedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

Patients with ischemic heart disease and candidates for PCI or acute coronary syndrome who referred for coronary angiography with a possible clinical indication for PCI
Patients with acute coronary syndrome and candidates for PCI
Patients have undergone elective and non-emergency PCI
Consent to participate in the present study

Exclusion Criteria

using the oral steroid drugs or NSAIDs except aspirin
Active malignancy or infection
History of Myelodysplasia
Severe Hepatic dysfunction (AST or ALT more than 3 times UMN)
Pregnancy
Renal dysfunction (serum creatinine more than 2.5 mg/dL or undergoing dialysis)
History of revascularization (PCI or CABG)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum levels of hs-Troponin-I. Timepoint: before PCI and 24 hours after PCI. Method of measurement: Immunoassay.;Serum levels of hs-CRP. Timepoint: before PCI and 24 hours after PCI. Method of measurement: Immunoassay.

Secondary Outcome Measures

Name	Time	Method
Stent thrombosis. Timepoint: 30 days after PCI. Method of measurement: Observation, ECG, Echocardiography.