The Role of Clinical Pharmacist in Management of DDIs in CHF Patients

Not Applicable

• Conditions: Chronic Heart Failure
• Interventions: Behavioral: Advice on DDIs

• Registration Number: NCT01855165
• Lead Sponsor: The University Clinic of Pulmonary and Allergic Diseases Golnik

Brief Summary

Drug-drug interactions (DDIs) are common in patients with chronic heart failure (CHF) and their incidence increases with the number of drugs that the patients are prescribed for treatment of their condition. Data bases often detect DDIs that are of high clinical relevance. The investigators have performed this study in order to detect clinically significant DDIs and to diminish their occurrence by sending notification about DDIs to attending physician.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-04
• Status Verified: 2013-05
• Study First Submitted: 2013-05-06
• Study First Submitted QC: 2013-05-15
• Last Update Submitted: 2013-05-15
• Study First Posted: 2013-05-16
• Last Update Posted: 2013-05-16
• Primary Completion: 2013-12
• Study Completion: 2013-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients admitted with diagnosis of CHF I50.0 - I50.9 and I11.0 - I11.9 (ICD-10)
• patients treated with at least two drugs

Exclusion Criteria

• Patients admitted to other conditions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Advice on DDIs	Advice on DDIs	Attending physician will be randomly assigned to intervention arm care as usual; in the intervention arm, he/she will receive advice about DDIs between medications prescribed to patients on top of general heart failure advice.

Primary Outcome Measures

Name	Time	Method
To assess the difference in frequency and severity of clinically significant DDIs in control arm and interventional arm between admission and discharge	90 days	We will measure the difference in clinically significant DDIs between admission and discharge. The doctors in control group will not receive the advice about DDIs between drugs prescribed to patient, while the doctors in interventional group will. With this will will assess the impact of the advice in the occurence of DDIs between admission and discharge for both groups.

Trial Locations

Locations (1)

University Clinic Golnik; 🇸🇮 Golnik, Slovenia