Non-invasive Respiratory Mechanics Assessment During Spontaneous / Assisted Breathing: The ERNI (Elastance, Resistance, Non Invasive Measurements) Study

University of Turin, Italy0 sites15 target enrollmentFebruary 2012

ConditionsRespiratory Insufficiency

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Respiratory Insufficiency
Sponsor: University of Turin, Italy
Enrollment: 15
Primary Endpoint: Non-invasive respiratory mechanics measurement
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The study aims to assess the agreement between respiratory mechanics parameters measured noninvasively by means of brief airways occlusions at the beginning of inspiration and the reference parameters obtained with standard techniques of esophageal and gastric pressure under static and dynamic conditions in a mixed population of ICU patients mechanically ventilated in pressure support ventilation mode.

Registry

clinicaltrials.gov

Start Date

February 2012

End Date

November 2012

Last Updated

14 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

University of Turin, Italy

Responsible Party

Principal Investigator

Marco Ranieri

MD Professor

University of Turin, Italy

Eligibility Criteria

Inclusion Criteria

•intact respiratory drive;
•PaO2/FiO2 ratio \> 150 with a positive end-expiratory pressure (PEEP) ≤ 8 cmH2O;
•pH between 7.35 and 7.45;
•patient alert, conscious, and cooperative with a Glasgow Coma Scale ≥ 10.