Insufficient cellular oxygen in ICU patients with anaemia: the INOX ICU-2 Study

Completed

• Conditions: anemie bij kritisch zieke mensen op de IC; anaemia; anemia

• Registration Number: NL-OMON50343
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 209

Inclusion Criteria

During the pilot study: all adult patients, admitted to the intensive care unit
with [Hb] below 6,3 mmol/l, who are planned to undergo a transfusion of red
blood cells.
During the prospective cohort study: all patients with a Hb below 6.3 mmol/l in
whom an arterial catheter is in place and in whom a red cell transfusion is
planned.

Exclusion Criteria

-adults without an legal representative for the informed consent,
-less than 18 years old,
-patients in need of emergency red cell transfusion e.g. bleeding,
-porphyria,
-known photodermatosis,
-ICU stay <24hrs,
-pregnant or breast feeding women since there is no adequate data from the use
of ALA in pregnant or breast feeding women,
-hypersensitivity to the active substance or to the plaster material of ALA,
-insufficient comprehensibility of the Dutch language

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified