Cardiac, Pulmonary and Diaphragm Sonography for the Early Diagnosis of the Different Etiologies Underlying Failure of Weaning From Mechanical Ventilation

• Conditions: Mechanical Ventilation; Following Heart or Abdominal Surgery

• Registration Number: NCT03261440
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

Weaning patients off ventilation in an ICU is sometimes difficult, because of three major inter-related etiologies: impaired lung, heart and diaphragm function. In this context, ultrasonography during tests to wean patients off ventilation could make it possible to diagnose cardiac dysfunction, a loss of pulmonary aeration or diaphragm dysfunction and thus reduce the number of failures at extubation.

The study will be carried out in 100 patients on mechanical ventilation following abdominal or heart surgery, who will have echocardiography, and pulmonary and diaphragm ultrasonography.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11
• Status Verified: 2017-08
• Study First Submitted: 2017-08-23
• Study First Submitted QC: 2017-08-23
• Last Update Submitted: 2017-08-23
• Study First Posted: 2017-08-25
• Last Update Posted: 2017-08-25
• Primary Completion: 2017-11
• Study Completion: 2017-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients on mechanical ventilation for at least 48 hours
• Age ≥ 60 years
• Patients who have undergone abdominal or heart surgery

Exclusion Criteria

• Patients with a known neuromuscular disease
• Patients younger than 60 years
• Duration of mechanical ventilation <48h
• Non-surgical patients
• Patients with severe COPD

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Echocardiography	At baseline
Diaphragm ultrasonography	At baseline
Lung ultrasonography	At baseline

Trial Locations

Locations (1)

CHU Dijon Bourgogne; 🇫🇷 Dijon, France