NCT02826811Unknown不适用
Role of Anti-BK Virus Neutralizing Antibodies (BKV) as a Prognostic Marker for the Development of Nephropathy BK
University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 170 人开始时间: 2016年7月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 170
- 试验地点
- 1
- 主要终点
- Quantification of anti-BKV
研究概览
简要总结
BKV nephropathy (BKV) is one of the most frequent complications of kidney transplantation.
In the absence of specific anti-BKV treatment, pre-emptive reduction of immunosuppression is the main strategy that has proven effective in reducing the risk of BKVN. However, it exposes a transplant rejection risk estimated between 4 and 14% according to studies.
Despite the pre-emptive reduction of immunosuppression, a significant number of patients continue to progress towards BKVN suggesting that pre-emptive strategy is late. It's therefore urgent to develop new prognostic markers to identify earlier and more effectively patients with a higher risk of developing BKVN.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient over 18 years
- •Grafted kidney patient between 1 July 2012 and 31 July 2014 at Strasbourg University Hospital with regular monitoring
排除标准
- •Patient under 18 years
结局指标
主要结局
Quantification of anti-BKV
时间窗: up to 12 months post-transplantation
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
进行中（未招募）
不适用
Prediction of BKvirus Nephropathy Risk by the NEPHROVIR Method in Kidney Transplant Patients With BKvirus ViremiaBK Virus InfectionNephropathyKidney TransplantationNCT05026021Assistance Publique - Hôpitaux de Paris41
招募中
不适用
New Therapeutic Approach Against BK Virus Infection Based on Monoclonal AntibodiesBK Virus InfectionNCT05264259University Hospital, Strasbourg, France100
Unknown
4 期
Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal TransplantDisorder Related to Renal TransplantationImmunosuppression Related Infectious DiseaseVirus DiseasesNCT01289301Hannover Medical School124
已完成
不适用
Evaluation of Renal Pretransplant Serology for BK Virus on the Risk of Post-transplant Viral ReactivationBK Virus NephropathyRisk FactorKidney TransplantationNCT04506060Centre Hospitalier Universitaire, Amiens378
Unknown
不适用
BK Viremia After Renal TransplantationTerminal Renal FailureBK Virus InfectionNCT00684372Karolinska University Hospital100