NCT05264259招募中不适用
New Therapeutic Approach Against BK Virus Infection Based on Monoclonal Antibodies
University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年9月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Ability of the isolated monoclonal antibodies to neutralize all 3 BKV genotypes
研究概览
简要总结
BK virus (BKV) infection has a major negative impact on transplant recipients. No BKV-specific antiviral therapy is available, so there is an urgent need to develop new anti-BKV preventive and therapeutic strategies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BK positive
- •ok to participed to research
排除标准
- •under guardianship
- •under curatorship
- •opposed to research
- •deprived of liberty
结局指标
主要结局
Ability of the isolated monoclonal antibodies to neutralize all 3 BKV genotypes
时间窗: 5 years
The neutralization titer will be defined as the dilution of the sample that produced 50% inhibition of pseudovirion infectivity (IC50)
次要结局
未报告次要终点
研究者
研究点 (1)
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