Effectiveness of Fluoride Varnish Application as Cariostatic Agent in Irradiated Head and Neck Cancer Patients

Phase 1

Recruiting

• Conditions: Dental caries prevention in irradiated head and neck patients; Fluoride Vanish; Head and Neck Cancer; Dental caries; Radiation

• Registration Number: TCTR20190327001
• Lead Sponsor: Institute of Medical Research and Technology Assessment, Department of Medical Service

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-03-27
• Study Completion: 2021-03-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Diagnosed with head and neck squamous cell carcinoma or salivary gland cancer
Intends to recieve external beam radiation therapy with curative intent
3 or more healthy or treated teeth on each side (Left and Right)of the mandible Or maxilla after completion of the pre-radiotherapy dental extraction

Exclusion Criteria

Patients in palliative care or end-of-life care
Patients participating in another research dealing with dental care
Contra-indication to Fluoride vanish

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Caries increment end point at 12 month follow up International Caries Detection and Assessment System (ICDAS)

Secondary Outcome Measures

Name	Time	Method
DMFT increment 3,6,9,12 months International Caries Detection and Assessment System (ICDAS)