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Effect of melatonin supplementation in treatment of diabetic hemodialysis patients

Phase 3
Conditions
Hemodialysis.
Chronic kidney disease (CKD)
Registration Number
IRCT20170513033941N31
Lead Sponsor
Kashan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
60
Inclusion Criteria

diabetic hemodialysis patients
Individuals aged 18 to 80 years old

Exclusion Criteria

Patients with infectious, inflammatory and malignant diseases
those taking melatonin supplements, antioxidant and/or anti-inflammatory supplements within 3 months prior to enrollment in the study
the night shift workers
subjects taking immunosuppressive and antibiotics medications
unwillingness to cooperate

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Insulin. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Elisa kit.;Insulin resistance. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Calculation using HOMA formula.;Insulin sensitivity. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Calculation using formula.
Secondary Outcome Measures
NameTimeMethod
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