Endomyocardial Botulinum Toxin Injection Can Decrease the Number of Episodes of VT Storm: Pilot Study

Meshalkin Research Institute of Pathology of Circulation1 site in 1 country15 target enrollmentJune 2013

ConditionsVT Storm

InterventionsBT injection

DrugsBT injection

Overview

Phase: Phase 1
Intervention: BT injection
Conditions: VT Storm
Sponsor: Meshalkin Research Institute of Pathology of Circulation
Enrollment: 15
Locations: 1
Primary Endpoint: number of episodes of VT Storm
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this prospective non-randomized study was to assess the efficacy and safety of endomyocardial botulinum toxin injection in left ventricle for preventing episodes of VT Storm.

Registry

clinicaltrials.gov

Start Date

June 2013

End Date

January 2016

Last Updated

10 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Meshalkin Research Institute of Pathology of Circulation

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•3 or more episodes of ventricular tachycardia within 24 hours

Exclusion Criteria

•Failure to provide informed consent.
•Non-cardiac illness with a life expectancy of less than 3 year
•Non-cardiac illness imposing substantial operative mortality
•Current participation in another clinical trial in which a patient is taking an investigational drug or receiving an investigational medical device